SMALL MOLECULE DRUG DISCOVERY TARGETING THE JAK-STAT PATHWAY

Small molecule drug discovery targeting the JAK-STAT pathway

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway functions as a central hub for transmitting signals from more than 50 cytokines, playing a pivotal role in maintaining hematopoiesis, immune balance, and tissue homeostasis.Dysregulation of this pathway has been implicated in various diseases, including immunodefic

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